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CC-90002
😃Good
Catalog No. T76732Cas No. 2085844-54-6
Alias CC90002, CC 90002
CC-90002 is a humanized monoclonal antibody targeting CD47 that inhibits CD47-SIRPα interactions, suitable for studying hematologic malignancies such as leukemia.
CC-90002
CC-90002
😃Good
Purity: 95%
Catalog No. T76732Alias CC90002, CC 90002Cas No. 2085844-54-6
CC-90002 is a humanized monoclonal antibody targeting CD47 that inhibits CD47-SIRPα interactions, suitable for studying hematologic malignancies such as leukemia.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $619 | - | In Stock | |
| 10 mg | $993 | - | In Stock | |
| 25 mg | $1,470 | - | In Stock | |
| 50 mg | $1,980 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95.8% (SDS-PAGE); 95.4% (SEC-HPLC)
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Product Introduction
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Chemical Properties
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| Description | CC-90002 is a humanized monoclonal antibody targeting CD47 that inhibits CD47-SIRPα interactions, suitable for studying hematologic malignancies such as leukemia. |
| In vitro | CC-90002 exhibits high affinity for CD47, with a Kd value reaching the sub-nanomolar range [1]. CC-90002 blocks the interaction between CD47 and SIRPα, with an IC50 value in the sub-nanomolar range [1]. CC-90002 demonstrates concentration-dependent inhibitory activity against acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) cell lines [1]. |
| In vivo | CC-90002 exhibits significant dose-dependent antitumor activity and achieves marked tumor regression in tumor xenograft models [1]. |
| Synonyms | CC90002, CC 90002 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CD47 |
| Molecular Weight | 146.53 kDa |
| Cas No. | 2085844-54-6 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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