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DL-Willardiine

🥰Excellent
Catalog No. T50094Cas No. 19772-76-0
Alias 2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid

DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) is an unnatural amino acid, a derivative of glutamate. It is an agonist of mGluR5, which regulates the activity of enzymes involved in neurotransmitter synthesis and catabolism, and affects the activity of ion channels and other membrane proteins.

DL-Willardiine
Other Forms of DL-Willardiine:
(S)-WillardiineT1345621416-43-3
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DL-Willardiine

🥰Excellent
Purity: 99.83%
Catalog No. T50094Alias 2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acidCas No. 19772-76-0
DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) is an unnatural amino acid, a derivative of glutamate. It is an agonist of mGluR5, which regulates the activity of enzymes involved in neurotransmitter synthesis and catabolism, and affects the activity of ion channels and other membrane proteins.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$86In StockIn Stock
2 mg$129In StockIn Stock
5 mg$198In StockIn Stock
10 mg$298In StockIn Stock
25 mg$475In StockIn Stock
50 mg$672In StockIn Stock
100 mg$912In StockIn Stock
200 mg$1,190In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.83%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
DL-Willardiine (2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid) is an unnatural amino acid, a derivative of glutamate. It is an agonist of mGluR5, which regulates the activity of enzymes involved in neurotransmitter synthesis and catabolism, and affects the activity of ion channels and other membrane proteins.
Synonyms2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid
Chemical Properties
Molecular Weight199.16
FormulaC7H9N3O4
Cas No.19772-76-0
SmilesC(C(C(O)=O)N)N1C(=O)NC(=O)C=C1
Relative Density.1.501 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: < 1.99 mg/mL (10 mM, insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.0211 mL25.1054 mL50.2109 mL251.0544 mL
5 mM1.0042 mL5.0211 mL10.0422 mL50.2109 mL
10 mM0.5021 mL2.5105 mL5.0211 mL25.1054 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Gria1 - glutamate ionotropic receptor AMPA type subunit 1 (Norway rat)DL-WillardiineDLWillardiineDL Willardiine
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