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NY2267

Name: NY2267
Brand: TargetMol
SKU: T9093
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9093Cas No. 886053-73-2

Alias Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester

NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester) is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.

NY2267

🥰Excellent

Purity: 99.27%

Catalog No. T9093Alias Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl esterCas No. 886053-73-2

Pack Size	Price	Availability
1 mg	$89	In Stock
5 mg	$197	In Stock
10 mg	$313	In Stock
25 mg	$553	In Stock
50 mg	$787	In Stock
100 mg	$1,070	In Stock
1 mL x 10 mM (in DMSO)	$278	In Stock

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Purity:99.27%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester) is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.
Targets&IC50	c-Myc-Max:36.5 μM
Synonyms	Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester

Chemical Properties

Molecular Weight	637.76
Formula	C₃₈H₄₃N₃O₆
Cas No.	886053-73-2
Smiles	COc1ccc(CN(C(C(=O)NC2CCCCC2)c2ccc3cc(OCC(=O)OC(C)(C)C)ccc3c2)C(=O)c2ccccn2)cc1
Relative Density.	1.23 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (392.00 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5680 mL	7.8399 mL	15.6799 mL	78.3994 mL
5 mM	0.3136 mL	1.5680 mL	3.1360 mL	15.6799 mL
10 mM	0.1568 mL	0.7840 mL	1.5680 mL	7.8399 mL
20 mM	0.0784 mL	0.3920 mL	0.7840 mL	3.9200 mL
50 mM	0.0314 mL	0.1568 mL	0.3136 mL	1.5680 mL
100 mM	0.0157 mL	0.0784 mL	0.1568 mL	0.7840 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc