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Zovostotug
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Catalog No. T80720Cas No. 2756228-84-7
Alias OR-2805
Zovostotug is a human monoclonal antibody targeting human CD163 (Scavenger Receptor Cysteine-Rich Type 1 Protein M130). This product binds specifically to CD163, aiming to modulate the function of tumor-associated macrophages (TAMs) and improve the immunosuppressive tumor microenvironment. It serves as an important pharmacological tool for researching immunotherapy of solid tumors and macrophage phenotype switching.
Zovostotug
Zovostotug
Copy Product Info😃Good
Catalog No. T80720Alias OR-2805Cas No. 2756228-84-7
Zovostotug is a human monoclonal antibody targeting human CD163 (Scavenger Receptor Cysteine-Rich Type 1 Protein M130). This product binds specifically to CD163, aiming to modulate the function of tumor-associated macrophages (TAMs) and improve the immunosuppressive tumor microenvironment. It serves as an important pharmacological tool for researching immunotherapy of solid tumors and macrophage phenotype switching.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Zovostotug is a human monoclonal antibody targeting human CD163 (Scavenger Receptor Cysteine-Rich Type 1 Protein M130). This product binds specifically to CD163, aiming to modulate the function of tumor-associated macrophages (TAMs) and improve the immunosuppressive tumor microenvironment. It serves as an important pharmacological tool for researching immunotherapy of solid tumors and macrophage phenotype switching. |
| In vitro | In vitro assays demonstrate that Zovostotug exhibits high specificity for CD163-expressing myeloid cells and effectively binds to the surface of M2-type macrophages, enabling the precise identification and targeting of immunosuppressive cell populations [1]. |
| In vivo | In pharmacological studies using preclinical models, systemic administration of Zovostotug targets CD163-positive cell populations within the tumor microenvironment, leading to a reduction in tumor burden and a measurable shift in the intratumoral immune landscape [1]. |
| Synonyms | OR-2805 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CD163 |
| Cas No. | 2756228-84-7 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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