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TH1085

🥰Excellent
Catalog No. T60034Cas No. 1002801-51-5
Alias TH10785

TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).

TH1085

TH1085

🥰Excellent
Purity: 99.99%
Catalog No. T60034Alias TH10785Cas No. 1002801-51-5
TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$44In StockIn Stock
2 mg$62In StockIn Stock
5 mg$98In StockIn Stock
10 mg$163In StockIn Stock
25 mg$313In StockIn Stock
50 mg$497In StockIn Stock
100 mg$723In StockIn Stock
500 mg$1,520-In Stock
1 mL x 10 mM (in DMSO)$116In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.99%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).
SynonymsTH10785
Chemical Properties
Molecular Weight267.37
FormulaC17H21N3
Cas No.1002801-51-5
SmilesC1CC1c1nc(NC2CCCCC2)c2ccccc2n1
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (187.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7401 mL18.7007 mL37.4014 mL187.0068 mL
5 mM0.7480 mL3.7401 mL7.4803 mL37.4014 mL
10 mM0.3740 mL1.8701 mL3.7401 mL18.7007 mL
20 mM0.1870 mL0.9350 mL1.8701 mL9.3503 mL
50 mM0.0748 mL0.3740 mL0.7480 mL3.7401 mL
100 mM0.0374 mL0.1870 mL0.3740 mL1.8701 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TH-1085TH1085TH-10785TH 1085TH 10785phenylalanineInhibitorinhibitglycineenzymeDNA oxidative lesionsDNA glycosylase 1 (OGG1)8-oxoguanine DNA glycosylase 1 (OGG1)
Related Tags: buy TH1085 | purchase TH1085 | TH1085 cost | order TH1085 | TH1085 chemical structure | TH1085 formula | TH1085 molecular weight
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