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Myristoleic acid

Name: Myristoleic acid
Brand: TargetMol
SKU: T41288
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T41288Cas No. 544-64-9

Alias cis-9-tetradecenoic acid, 9-Tetradecenoic acid, (Z)-Tetradec-9-enoic acid

Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.

Myristoleic acid

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Purity: 99.65%

Catalog No. T41288Alias cis-9-tetradecenoic acid, 9-Tetradecenoic acid, (Z)-Tetradec-9-enoic acidCas No. 544-64-9

Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$36	In Stock	In Stock
25 mg	$58	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.65%

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Product Introduction

Bioactivity

Description	Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.
In vitro	Myristoleic acid induces both necrosis (100 μg/mL, 81.8%) and apoptosis (100 μg/mL, 89.5%) in LNCaP cells [1]. Myristoleic acid inhibited RANKL-induced osteoclast formation in vitro, especially, at later stages of differentiation [2].
In vivo	Myristoleic acid (2 mg/kg, IP every 24 h for 4 days) inhibits RANKL-induced bone loss and osteoclast formation in mice [2].
Synonyms	cis-9-tetradecenoic acid, 9-Tetradecenoic acid, (Z)-Tetradec-9-enoic acid

Chemical Properties

Molecular Weight	226.35
Formula	C₁₄H₂₆O₂
Cas No.	544-64-9
Smiles	CCCC\C=C/CCCCCCCC(O)=O
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (441.79 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (14.58 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4179 mL	22.0897 mL	44.1794 mL	220.8968 mL
5 mM	0.8836 mL	4.4179 mL	8.8359 mL	44.1794 mL
10 mM	0.4418 mL	2.2090 mL	4.4179 mL	22.0897 mL
20 mM	0.2209 mL	1.1045 mL	2.2090 mL	11.0448 mL
50 mM	0.0884 mL	0.4418 mL	0.8836 mL	4.4179 mL
100 mM	0.0442 mL	0.2209 mL	0.4418 mL	2.2090 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc