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meso-Dihydroguaiaretic acid

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Catalog No. TN1581Cas No. 66322-34-7
Alias meso-DGA

meso-Dihydroguaiaretic acid is a natural lignan exhibiting multiple biological activities, including the inhibition of proliferation in ACC375, COS, and HeLa cells.

meso-Dihydroguaiaretic acid

meso-Dihydroguaiaretic acid

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Purity: 98.46%
Catalog No. TN1581Alias meso-DGACas No. 66322-34-7
meso-Dihydroguaiaretic acid is a natural lignan exhibiting multiple biological activities, including the inhibition of proliferation in ACC375, COS, and HeLa cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$400-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:98.46%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
meso-Dihydroguaiaretic acid is a natural lignan exhibiting multiple biological activities, including the inhibition of proliferation in ACC375, COS, and HeLa cells.
Targets&IC50
Ishikawa cells:45.46 μM, A2780 cells:27.17 μM
Synonymsmeso-DGA
Chemical Properties
Molecular Weight330.42
FormulaC20H26O4
Cas No.66322-34-7
SmilesC([C@@H]([C@@H](CC1=CC(OC)=C(O)C=C1)C)C)C2=CC(OC)=C(O)C=C2
Relative Density.1.121 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (242.12 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0265 mL15.1323 mL30.2645 mL151.3226 mL
5 mM0.6053 mL3.0265 mL6.0529 mL30.2645 mL
10 mM0.3026 mL1.5132 mL3.0265 mL15.1323 mL
20 mM0.1513 mL0.7566 mL1.5132 mL7.5661 mL
50 mM0.0605 mL0.3026 mL0.6053 mL3.0265 mL
100 mM0.0303 mL0.1513 mL0.3026 mL1.5132 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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