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Vamikibart

(Synonyms: EBI-031, EBI031, EBI 031) Copy Product Info
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Synonyms: EBI-031, EBI031, EBI 031

Catalog No. T80564 Copy Product Info
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Vamikibart (RG6179) is a humanized monoclonal antibody targeting interleukin-6 (IL-6). It antagonizes IL-6-mediated pro-inflammatory signaling to effectively inhibit uveitic macular edema (UME) and reduce retinal leakage. In clinical studies, Vamikibart administered via intravitreal injection significantly decreases anterior chamber cell density, demonstrating potent intraocular anti-inflammatory effects.

Vamikibart

Cas No. 2744320-12-3
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247-In Stock
5 mg$697-In Stock
10 mg$1,080-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:98.1% (SDS-PAGE); 98.0% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Vamikibart (RG6179) is a humanized monoclonal antibody targeting interleukin-6 (IL-6). It antagonizes IL-6-mediated pro-inflammatory signaling to effectively inhibit uveitic macular edema (UME) and reduce retinal leakage. In clinical studies, Vamikibart administered via intravitreal injection significantly decreases anterior chamber cell density, demonstrating potent intraocular anti-inflammatory effects.
SynonymsEBI-031, EBI031, EBI 031
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-6
Chemical Properties
Molecular Weight145.95 kDa
Cas No.2744320-12-3
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature.

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