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Vamikibart (RG6179) is a humanized monoclonal antibody targeting interleukin-6 (IL-6). It antagonizes IL-6-mediated pro-inflammatory signaling to effectively inhibit uveitic macular edema (UME) and reduce retinal leakage. In clinical studies, Vamikibart administered via intravitreal injection significantly decreases anterior chamber cell density, demonstrating potent intraocular anti-inflammatory effects.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | - | In Stock | |
| 5 mg | $697 | - | In Stock | |
| 10 mg | $1,080 | - | In Stock |
| Description | Vamikibart (RG6179) is a humanized monoclonal antibody targeting interleukin-6 (IL-6). It antagonizes IL-6-mediated pro-inflammatory signaling to effectively inhibit uveitic macular edema (UME) and reduce retinal leakage. In clinical studies, Vamikibart administered via intravitreal injection significantly decreases anterior chamber cell density, demonstrating potent intraocular anti-inflammatory effects. |
| Synonyms | EBI-031, EBI031, EBI 031 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-6 |
| Molecular Weight | 145.95 kDa |
| Cas No. | 2744320-12-3 |
| Isotype | Human IgG2 kappa |
| Recommended Isotype Control |
| Storage | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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