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D-Isoleucine

Name: D-Isoleucine
Brand: TargetMol
SKU: T9143
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T9143Cas No. 319-78-8

Alias (R)-Isoleucine, (2R,3R)-2-Amino-3-methylpentanoic acid

D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine.

D-Isoleucine

🥰Excellent

Purity: 99.16%

Catalog No. T9143Alias (R)-Isoleucine, (2R,3R)-2-Amino-3-methylpentanoic acidCas No. 319-78-8

Pack Size	Price	Availability
25 mg	$30	In Stock
50 mg	$51	In Stock
100 mg	$80	In Stock
500 mg	$178	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Batch Information

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Purity:99.16%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine.
Synonyms	(R)-Isoleucine, (2R,3R)-2-Amino-3-methylpentanoic acid

Chemical Properties

Molecular Weight	131.17
Formula	C₆H₁₃NO₂
Cas No.	319-78-8
Smiles	CC[C@@H](C)[C@@H](N)C(O)=O
Relative Density.	1.035g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (419.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.6237 mL	38.1185 mL	76.2369 mL	381.1847 mL
5 mM	1.5247 mL	7.6237 mL	15.2474 mL	76.2369 mL
10 mM	0.7624 mL	3.8118 mL	7.6237 mL	38.1185 mL
20 mM	0.3812 mL	1.9059 mL	3.8118 mL	19.0592 mL
50 mM	0.1525 mL	0.7624 mL	1.5247 mL	7.6237 mL
100 mM	0.0762 mL	0.3812 mL	0.7624 mL	3.8118 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc