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Anti-CD300A Antibody (9F620)
😃Good
Catalog No. TMAY-02353
Alias IRp60, IRC2, IRC1/IRC2, IRC1, IGSF12, CMRF35-H9, CMRF-35-H9, CMRF35H9, CMRF35-H, CMRF-35H, CMRF35H, CLM-8, CD300a molecule
Anti-CD300A Antibody (9F620) is a Mouse antibody targeting CD300A. Anti-CD300A Antibody (9F620) can be used in FCM.
Anti-CD300A Antibody (9F620)
Anti-CD300A Antibody (9F620)
😃Good
Catalog No. TMAY-02353Alias IRp60, IRC2, IRC1/IRC2, IRC1, IGSF12, CMRF35-H9, CMRF-35-H9, CMRF35H9, CMRF35-H, CMRF-35H, CMRF35H, CLM-8, CD300a molecule
Anti-CD300A Antibody (9F620) is a Mouse antibody targeting CD300A. Anti-CD300A Antibody (9F620) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD300A Antibody (9F620) is a Mouse antibody targeting CD300A. Anti-CD300A Antibody (9F620) can be used in FCM. |
| Alias | IRp60, IRC2, IRC1/IRC2, IRC1, IGSF12, CMRF35-H9, CMRF-35-H9, CMRF35H9, CMRF35-H, CMRF-35H, CMRF35H, CLM-8, CD300a molecule |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 9F620 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD300A expression on Human whole blood monocytes. Cells were stained with purified anti-Human CD300A, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD300A (rh CD300A; TMPY-02013; Q9UGN4-1; Met1-Gln178). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CMRF35-like molecule 8, also known as CD300 antigen-like family member A, CMRF35-H9, Immunoglobulin superfamily member 12, Inhibitory receptor protein 60, NK inhibitory receptor, CD300a and CMRF35H, is a single-pass type I membrane protein which belongs to the CD300 family. The CD300 family of myeloid immunoglobulin receptors includes activating ( CD300b, CD300e ) and inhibitory members ( CD300a, CD300f ), as well as molecules presenting a negative charge within their transmembrane domain ( CD300c, CD300d ). CD300A / IGSF12 is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. It contains oneIg-like V-type ( immunoglobulin-like ) domain. CD300A / IGSF12 is an inhibitory receptor that may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells. CD300c signaling is partially mediated by a direct association with the immune receptor tyrosine-based activation motif-bearing adaptor FcεRγ. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from plasmacytoid dendritic cells (pDCs). |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD300A Protein (TMPY-02013) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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