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Ibalizumab

🥰Excellent
Catalog No. T76687Cas No. 680188-33-4
Alias TNX-355, TMB-355

Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and may be used to maintain normal immune function.

Ibalizumab

Ibalizumab

🥰Excellent
Purity: 96.7% (SDS-PAGE); 97.7% (SEC-HPLC)
Catalog No. T76687Alias TNX-355, TMB-355Cas No. 680188-33-4
Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and may be used to maintain normal immune function.
Pack SizePriceAvailabilityQuantity
1 mg$788In Stock
5 mg$1,980In Stock
10 mg$2,670In Stock
25 mg$3,960In Stock
50 mg$5,350In Stock
100 mg$7,220In Stock
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Batch Information

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Concentration:4.19 mg/mL
Purity:96.7% (SDS-PAGE); 97.7% (SEC-HPLC)
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Resource Download

COA SDS-PAGE SEC-HPLC Instruction Manual of Inhibitory Antibody

Product Introduction

Bioactivity
Description
Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4 receptor.Ibalizumab has anti-HIV-1 infectious activity and may be used to maintain normal immune function.
SynonymsTNX-355, TMB-355
Chemical Properties
Molecular Weight147.3 kDa
Cas No.680188-33-4
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TNX355TNX 355TMB355TMB 355IbalizumabHIVProteaseHIV ProteaseHIVCD4
Related Tags: buy Ibalizumab | purchase Ibalizumab | Ibalizumab cost | order Ibalizumab | Ibalizumab chemical structure | Ibalizumab molecular weight
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