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Arecaidine
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Catalog No. TN1398Cas No. 499-04-7
Arecaidine is an alkaloid naturally present in areca nuts that functions as a γ-aminobutyric acid (GABA) reuptake inhibitor, displaying structural similarity to other GABA uptake inhibitors and demonstrating sedative effects in murine models, as well as protective activity against lethality induced by GABAA receptor antagonists, thereby supporting its use in neuropharmacological and inhibitory neurotransmission research.
Arecaidine
😃Good
Purity: 99.76%
Catalog No. TN1398Cas No. 499-04-7
Arecaidine is an alkaloid naturally present in areca nuts that functions as a γ-aminobutyric acid (GABA) reuptake inhibitor, displaying structural similarity to other GABA uptake inhibitors and demonstrating sedative effects in murine models, as well as protective activity against lethality induced by GABAA receptor antagonists, thereby supporting its use in neuropharmacological and inhibitory neurotransmission research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $32 | - | In Stock | |
| 5 mg | $73 | - | In Stock | |
| 10 mg | $123 | - | In Stock | |
| 25 mg | $198 | - | In Stock | |
| 50 mg | $297 | - | In Stock | |
| 100 mg | $453 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.76%
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Product Introduction
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Chemical Properties
Storage & Solubility Information
| Description | Arecaidine is an alkaloid naturally present in areca nuts that functions as a γ-aminobutyric acid (GABA) reuptake inhibitor, displaying structural similarity to other GABA uptake inhibitors and demonstrating sedative effects in murine models, as well as protective activity against lethality induced by GABAA receptor antagonists, thereby supporting its use in neuropharmacological and inhibitory neurotransmission research. |
| In vivo | Method: Arecaidine and guvacine were tested in vitro using cat spinal cord and cerebellar slices and administered intravenously, topically, or subcutaneously in cats and mice at doses up to 1 g/kg. Result: Arecaidine and guvacine inhibited GABA uptake and enhanced GABAergic inhibition in vitro, but showed minimal anticonvulsant or synaptic inhibitory effects in vivo[1]. |
| Molecular Weight | 141.17 |
| Formula | C7H11NO2 |
| Cas No. | 499-04-7 |
| Smiles | O=C(O)C1=CCCN(C)C1 |
| Relative Density. | 1.166g/cm3 |
| Color | White |
| Appearance | Solid |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: 200 mg/mL (1416.73 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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