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Anti-CAV1 Antibody (2M160)

(Synonyms: Caveolin-1, CAV 1, CAV) Copy Product Info
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Synonyms: Caveolin-1, CAV 1, CAV

Catalog No. TMAH-00146 Copy Product Info
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Anti-CAV1 Antibody (2M160) is an antibody targeting CAV1. Anti-CAV1 Antibody (2M160) can be used in ELISA,FCM,WB.
Anti-CAV1 Antibody
(2M160)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2087-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CAV1 Antibody (2M160) is an antibody targeting CAV1. Anti-CAV1 Antibody (2M160) can be used in ELISA,FCM,WB.
SynonymsCaveolin-1, CAV 1, CAV
Ig Type
Rabbit IgG
Clone
2M160
Reactivity
Human
Application
Recommended Dose
WB:1:500-1:2000; FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationGolgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Golgi apparatus, trans-Golgi network. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
Tissue SpecificitySkeletal muscle, liver, stomach, lung, kidney and heart (at protein level). Expressed in the brain.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundMay act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human CAV1
Antigen Species
Human
Gene Name
CAV1
Gene ID
Uniprot ID
Biology Area
Cancer, Cardiovascular, Tags & Cell Markers, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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