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Anti-B7-1 Antibody-FITC (2N313)

🥰Excellent
Catalog No. TMAY-03298F

Anti-B7-1 Antibody-FITC (2N313) is a FITC-conjugated Rabbit antibody targeting B7-1. Anti-B7-1 Antibody-FITC (2N313) can be used in FCM.

Anti-B7-1 Antibody-FITC (2N313)

Anti-B7-1 Antibody-FITC (2N313)

🥰Excellent
Catalog No. TMAY-03298F
Anti-B7-1 Antibody-FITC (2N313) is a FITC-conjugated Rabbit antibody targeting B7-1. Anti-B7-1 Antibody-FITC (2N313) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-B7-1 Antibody-FITC (2N313) is a FITC-conjugated Rabbit antibody targeting B7-1. Anti-B7-1 Antibody-FITC (2N313) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
2N313
Reactivity
Mouse
Verified Activity
Flow cytometric analysis of Mouse CD80 expression on LPS-stimulated BABL/c splenocytes. Cells were stained with FITC-conjugated anti-Mouse CD80. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
2 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD80/B7-1 (rM CD80/B7-1; TMPY-02307; Q00609-1; Met1-Lys245) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundThe B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
FITC
Others Formats
Unconjugated/APC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Mouse CD80/B7-1 Protein (TMPY-02307)
Antigen Species
Mouse
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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