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Anti-AKR1B1 Antibody (4W828)
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Catalog No. TMAY-01831
Alias MGC1804, AR, ALR2, ALDR1, aldo-keto reductase family 1, member B1 (aldose reductase), ADR
Anti-AKR1B1 Antibody (4W828) is a Rabbit antibody targeting AKR1B1. Anti-AKR1B1 Antibody (4W828) can be used in FCM.
Anti-AKR1B1 Antibody (4W828)
Anti-AKR1B1 Antibody (4W828)
😃Good
Catalog No. TMAY-01831Alias MGC1804, AR, ALR2, ALDR1, aldo-keto reductase family 1, member B1 (aldose reductase), ADR
Anti-AKR1B1 Antibody (4W828) is a Rabbit antibody targeting AKR1B1. Anti-AKR1B1 Antibody (4W828) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Human |
| Alias | MGC1804, AR, ALR2, ALDR1, aldo-keto reductase family 1, member B1 (aldose reductase), ADR |
| Ig Type | Rabbit IgG |
| Clone | 4W828 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human AKR1B1 expression on HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human AKR1B1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human AKR1B1 (rh AKR1B1; TMPY-02438; P15121; Met1-Phe316). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest in lens and retina. It is the first enzyme in the polyol pathway through which glucose is converted to sorbitol which is important for the function of various organs in the body, and has been implicated in the etiology of diabetic complications. AKR1B1 is quite abundant in the collecting tubule cells and thought to provide protection against hypertonic environment. Some human tissues contain AKR1B1 as well as AKR1B10, a closely related member of the aldo-keto reductase superfamily. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human AKR1B1 Protein (TMPY-02438) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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