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(Rac)-Idroxioleic acid

Name: (Rac)-Idroxioleic acid
Brand: TargetMol
SKU: T16075
Price: 52 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16075Cas No. 56472-29-8

Alias Minerval, 2-OHOA, 2-Hydroxyoleic acid

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization.

(Rac)-Idroxioleic acid

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Catalog No. T16075Alias Minerval, 2-OHOA, 2-Hydroxyoleic acidCas No. 56472-29-8

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$52	-	In Stock
5 mg	$106	-	In Stock
10 mg	$172	-	In Stock
25 mg	$355	-	In Stock
50 mg	$569	-	In Stock
1 mL x 10 mM (in DMSO)	$175	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:≥98%

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor properties that binds to the plasma membrane, altering lipid organization.
Targets&IC50	Jurkat cells:40 μM
In vitro	Minerval (25-50 μM; 72 hours) causes a marked and concentration-dependent increase in the proteolytic cleavage of PARP, a molecular marker of apoptosis. Minerval (25-75 μM; 72 hours) impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50: 40 μM)[1].
In vivo	In nude mice infected with Jurkat cells, Minerval significantly inhibits tumour growth[1].
Synonyms	Minerval, 2-OHOA, 2-Hydroxyoleic acid

Chemical Properties

Molecular Weight	298.46
Formula	C₁₈H₃₄O₃
Cas No.	56472-29-8
Smiles	C(CCC(C(O)=O)O)CCC/C=C\CCCCCCCC
Relative Density.	no data available

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (167.53 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3505 mL	16.7527 mL	33.5053 mL	167.5266 mL
5 mM	0.6701 mL	3.3505 mL	6.7011 mL	33.5053 mL
10 mM	0.3351 mL	1.6753 mL	3.3505 mL	16.7527 mL
20 mM	0.1675 mL	0.8376 mL	1.6753 mL	8.3763 mL
50 mM	0.0670 mL	0.3351 mL	0.6701 mL	3.3505 mL
100 mM	0.0335 mL	0.1675 mL	0.3351 mL	1.6753 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc