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Anti-Alix Antibody (5X926)
😃Good
Catalog No. TMAH-00054
Alias Programmed cell death 6-interacting protein, PDCD6IP, PDCD6-interacting protein, KIAA1375, Hp95, ALIX, ALG-2-interacting protein X, ALG-2-interacting protein 1, AIP1
Anti-Alix Antibody (5X926) is a Mouse antibody targeting Alix. Anti-Alix Antibody (5X926) can be used in ELISA, WB.
Anti-Alix Antibody (5X926)
Anti-Alix Antibody (5X926)
😃Good
Catalog No. TMAH-00054Alias Programmed cell death 6-interacting protein, PDCD6IP, PDCD6-interacting protein, KIAA1375, Hp95, ALIX, ALG-2-interacting protein X, ALG-2-interacting protein 1, AIP1
Anti-Alix Antibody (5X926) is a Mouse antibody targeting Alix. Anti-Alix Antibody (5X926) can be used in ELISA, WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA, WB Reactivity: Human |
| Alias | Programmed cell death 6-interacting protein, PDCD6IP, PDCD6-interacting protein, KIAA1375, Hp95, ALIX, ALG-2-interacting protein X, ALG-2-interacting protein 1, AIP1 |
| Ig Type | IgG2b |
| Clone | 5X926 |
| Reactivity | Human |
| Verified Activity | Western Blot -Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, PC-3 whole cell lysate, U87 whole cell lysate -All lanes: Alix antibody at 1:1000 -Secondary: Goat polyclonal to mouse IgG at 1/50000 dilution -Predicted band size: 30, 96 KDa -Observed band size: 96 KDa -Exposure time：5min |
| Application | ELISA, WB |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm, cytosol. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Secreted, extracellular exosome. Cell junction, tight junction. Midbody, Midbody ring. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Purity | >95% |
| Research Background | Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. May play a role in the regulation of both apoptosis and cell proliferation. Regulates exosome biogenesis in concert with SDC1/4 and SDCBP. By interacting with F-actin, PARD3 and TJP1 secures the proper assembly and positioning of actomyosin-tight junction complex at the apical sides of adjacent epithelial cells that defines a spatial membrane domain essential for the maintenance of epithelial cell polarity and barrier. (Microbial infection) Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function requires the interaction with CHMP4B. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as enveloped virus budding (HIV-1 and other lentiviruses). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Programmed cell death 6-interacting Protein |
| Antigen Species | Human |
| Gene ID | 10015 |
| Uniprot ID | |
| Biology Area | Others |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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