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Synonyms: YSAH1, YSA1H, YSA1, nudix (nucleoside diphosphate linked moiety X)-type motif 5, hYSAH1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-NUDT5 Antibody (4D504) is an antibody targeting NUDT5. Anti-NUDT5 Antibody (4D504) can be used in ELISA,FCM,WB. |
| Synonyms | YSAH1, YSA1H, YSA1, nudix (nucleoside diphosphate linked moiety X)-type motif 5, hYSAH1 |
| Ig Type | Rabbit IgG |
| Clone | 4D504 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:2000; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Widely expressed. Most abundant in liver. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human NUDT5 |
| Antigen Species | Human |
| Gene Name | NUDT5 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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