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Sikokianin A

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Catalog No. TN6420Cas No. 106293-99-6

Sikokianin A shows in vitro antiviral activity against HBsAg secretion.

Sikokianin A

Sikokianin A

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Catalog No. TN6420Cas No. 106293-99-6
Sikokianin A shows in vitro antiviral activity against HBsAg secretion.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$440InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Sikokianin A shows in vitro antiviral activity against HBsAg secretion.
In vitro
Two new C-3/C-3'' biflavanones, chamaejasmenin D (1) and isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), Sikokianin A (6), and chamaejasmenin C (7). METHODS AND RESULTS:Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively.
Chemical Properties
Molecular Weight556.523
FormulaC31H24O10
Cas No.106293-99-6
Smiles[H][C@@]1([C@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(O)cc1)[C@@]1([H])[C@H](Oc2cc(O)cc(O)c2C1=O)c1ccc(OC)cc1
Relative Density.1.521 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Sikokianin A
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