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Anti-IL-1R2 Antibody (8S151) (Synonyms: interleukin 1 receptor, type II)
Catalog No. TMAY-03767 Copy Product Info
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Anti-IL-1R2 Antibody (8S151) is a Rabbit antibody targeting IL-1R2. Anti-IL-1R2 Antibody (8S151) can be used in ELISA.
Anti-IL-1R2 Antibody (8S151)
Copy Product Info🥰Excellent
Catalog No. TMAY-03767
Synonyms interleukin 1 receptor, type II
Anti-IL-1R2 Antibody (8S151) is a Rabbit antibody targeting IL-1R2. Anti-IL-1R2 Antibody (8S151) can be used in ELISA.
Anti-IL-1R2 Antibody
(8S151)
(8S151)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-1R2 Antibody (8S151) is a Rabbit antibody targeting IL-1R2. Anti-IL-1R2 Antibody (8S151) can be used in ELISA. |
| Synonyms | interleukin 1 receptor, type II |
| Ig Type | Rabbit IgG |
| Clone | 8S151 |
| Reactivity | Rat |
| Specificity | Rat IL1R2 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat IL-1R2 / CD121b (rR IL-1R2 / CD121b; TMPY-02825; P43303; Met1-Glu355). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. The pleiotropic cytokine IL1 is produced to regulate the development and maintenance of the inflammatory responses and binds to specific plasma membrane receptors on cells. Two distinct types of IL1 receptors that can bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R1 contributes to IL-1 signaling, whereas the IL-1R2/CD121b has no signaling property and acts as a decoy for IL-1. IL-1R2/CD121b structurally consisting of a ligand-binding portion comprised of three Ig-like domains, a single transmembrane region, and a short cytoplasmic domain is expressed in a variety of cell types including B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Rat IL-1R2 / CD121b Protein (TMPY-02825) |
| Antigen Species | Rat |
| Biology Area | Neuroinflammation |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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