Shopping Cart
Remove All
Your shopping cart is currently empty
Emactuzumab
😃Good
Catalog No. T76776Cas No. 1448221-67-7
Alias RO 5509554, RG 7155
Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has antitumor activity and inhibits activation of colony-stimulating factor 1 receptor (CSF1R) Emactuzumab has a high affinity for CSF-1R with a Ki value of 0.2 nM. Emactuzumab blocks CSF-1R dimerization and can be used to study cancers such as diffuse tenosynovial giant cell tumor (dt-GCT).
Emactuzumab
😃Good
Catalog No. T76776Alias RO 5509554, RG 7155Cas No. 1448221-67-7
Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has antitumor activity and inhibits activation of colony-stimulating factor 1 receptor (CSF1R) Emactuzumab has a high affinity for CSF-1R with a Ki value of 0.2 nM. Emactuzumab blocks CSF-1R dimerization and can be used to study cancers such as diffuse tenosynovial giant cell tumor (dt-GCT).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $289 | In Stock | In Stock | |
| 5 mg | $745 | In Stock | In Stock | |
| 10 mg | $1,160 | - | In Stock | |
| 25 mg | $1,720 | - | In Stock | |
| 50 mg | $2,290 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:98.1% (SDS-PAGE); 97.3% (SEC-HPLC)
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has antitumor activity and inhibits activation of colony-stimulating factor 1 receptor (CSF1R) Emactuzumab has a high affinity for CSF-1R with a Ki value of 0.2 nM. Emactuzumab blocks CSF-1R dimerization and can be used to study cancers such as diffuse tenosynovial giant cell tumor (dt-GCT). |
| In vitro | RG7155 (30 μg/mL; 6 days) induces cell death of in vitro-differentiated human M2-like macrophages.[2] Inducing cell death, RG7155 (0-10 μg/mL; 7 days) inhibited the viability of CSF-1-differentiated macrophages with an IC50 of 0.3 nM.[2] Emactuzumab, with a high affinity binding to human and cynomolgus CSF-1R (Kd = 0.2 nM), effectively prevents CSF-1R dimerization.[2] |
| In vivo | Emactuzumab (0.1、1、10、30 and 100 mg/kg; i.v.; once; male cynomolgus monkey) increased CSF-1 concentration in serum.[2] RG7155 (0, 30, and 100 mg/kg; i.v.; once weekly; for 2 weeks; male and female cynomolgus) Efficiently reduced CSF-1R and CD68+163+ macrophages in the liver (Kupffer cells) and colon of cynomologus monkeys.[2] |
| Synonyms | RO 5509554, RG 7155 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CSF1R/M-CSFR/CD115 |
| Molecular Weight | 144.4 kDa |
| Cas No. | 1448221-67-7 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Emactuzumab | purchase Emactuzumab | Emactuzumab cost | order Emactuzumab | Emactuzumab chemical structure | Emactuzumab in vivo | Emactuzumab in vitro | Emactuzumab molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.