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Anti-VISTA Antibody (5Q796) is a Mouse antibody targeting VISTA. Anti-VISTA Antibody (5Q796) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-VISTA Antibody (5Q796) is a Mouse antibody targeting VISTA. Anti-VISTA Antibody (5Q796) can be used in FCM. |
Alias | V-set immunoregulatory receptor, VISTA, SISP1, PP2135, PD-1H, GI24, DD1α, DD1alpha, C10orf54, B7-H5, B7H5 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 5Q796 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human B7-H5(C10orf54) expression on human whole blood Granulocytes. Cells were stained with purified anti-Human B7-H5(C10orf54), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Granulocytes. |
Application | FCM |
Recommended Dose | FCM: 1:25-1:100 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. VSIR, or V-set immunoregulatory receptor, could be involved in the pathogenesis of chronic rhinosinusitis with nasal polyps. V-domain Immunoglobulin Suppressor of T cell Activation (VISTA) is an inhibitory immune-checkpoint molecule that suppresses CD4+ and CD8+ T cell activation when expressed on antigen-presenting cells. VSIR is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with VSIR include Ichthyosis, Congenital, Autosomal Recessive 6, and Monckeberg Arteriosclerosis. An important paralog of this gene is VSIG8. |
Conjucates | Unconjugated |
Others Formats | FITC/PE |
Antibody Types Available | 3 |
Immunogen | Recombinant Human VISTA Protein (TMPY-03219) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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