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Anti-CD54/ICAM-1 Antibody (R6-5-D6) is an inhibitory antibody that specifically targets human CD54/ICAM-1 and effectively blocks the interaction between CD54 and its ligand lymphocyte function-associated antigen 1 (LFA-1). It is suitable for research in inflammation and immunology.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $245 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $535 | 2-4 weeks | 2-4 weeks | |
| 10 mg | Preferential | 2-4 weeks | 2-4 weeks |
| Description | Anti-CD54/ICAM-1 Antibody (R6-5-D6) is an inhibitory antibody that specifically targets human CD54/ICAM-1 and effectively blocks the interaction between CD54 and its ligand lymphocyte function-associated antigen 1 (LFA-1). It is suitable for research in inflammation and immunology. |
| In vitro | Anti-CD54/ICAM-1 Antibody (R6-5-D6) induces the differentiation of human naive CD4+ T cells toward a regulatory T cell phenotype when administered at 10 μg/mL for 10 days [1]. Treatment with Anti-CD54/ICAM-1 Antibody (R6-5-D6) at 2–12 μg/mL for 15 minutes reduces basal adhesion in human umbilical vein endothelial cells (HUVECs) and inhibits the increase in adhesion induced by IL-1 or LPS stimulation [2]. |
| Clone | R6-5-D6 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | ICAM1/CD54 |
| Molecular Weight | 150 kDa |
| Isotype | Mouse IgG2a |
| Storage | Store at -20°C Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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