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Desthiobiotin-Iodoacetamide

🥰Excellent
Catalog No. T77878Cas No. 2924824-04-2

Desthiobiotin-Iodoacetamide is a functionalised reagent formed by linking desthiobiotin and iodoacetamide (IAM). It serves as a probe for investigating cysteine reactivity and may also function as an ADC Linker.

Desthiobiotin-Iodoacetamide

Desthiobiotin-Iodoacetamide

🥰Excellent
Purity: 99.35%
Catalog No. T77878Cas No. 2924824-04-2
Desthiobiotin-Iodoacetamide is a functionalised reagent formed by linking desthiobiotin and iodoacetamide (IAM). It serves as a probe for investigating cysteine reactivity and may also function as an ADC Linker.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$278-In Stock
5 mg$689In StockIn Stock
10 mg$1,130-In Stock
25 mg$1,930-In Stock
50 mg$2,720-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.35%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Desthiobiotin-Iodoacetamide is a functionalised reagent formed by linking desthiobiotin and iodoacetamide (IAM). It serves as a probe for investigating cysteine reactivity and may also function as an ADC Linker.
Chemical Properties
Molecular Weight424.28
FormulaC14H25IN4O3
Cas No.2924824-04-2
SmilesC(CCCCC(NCCNC(CI)=O)=O)[C@@H]1[C@H](C)NC(=O)N1
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 40 mg/mL (94.28 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (2.36 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3569 mL11.7847 mL23.5693 mL117.8467 mL
5 mM0.4714 mL2.3569 mL4.7139 mL23.5693 mL
10 mM0.2357 mL1.1785 mL2.3569 mL11.7847 mL
20 mM0.1178 mL0.5892 mL1.1785 mL5.8923 mL
50 mM0.0471 mL0.2357 mL0.4714 mL2.3569 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ADCLinker
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