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Tolmetin

Name: Tolmetin
Brand: TargetMol
SKU: T2550
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2550Cas No. 26171-23-3

Alias Tolectin

Tolmetin (Tolectin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of tolmetin is as a Cyclooxygenase Inhibitor. The chemical classification of tolmetin is Nonsteroidal Anti-inflammatory Compounds.

Tolmetin

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Purity: 99.74%

Catalog No. T2550Alias TolectinCas No. 26171-23-3

Pack Size	Price	Availability
50 mg	$33	In Stock
100 mg	$48	In Stock
200 mg	$68	In Stock
500 mg	$117	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.74%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Tolmetin (Tolectin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of tolmetin is as a Cyclooxygenase Inhibitor. The chemical classification of tolmetin is Nonsteroidal Anti-inflammatory Compounds.
Targets&IC50	COX-1 (human):0.35 μM (IC50), COX-2(human):0.82 μM (IC50)
Synonyms	Tolectin

Chemical Properties

Molecular Weight	257.28
Formula	C₁₅H₁₅NO₃
Cas No.	26171-23-3
Smiles	CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1
Relative Density.	1.1391 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (194.34 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8868 mL	19.4341 mL	38.8682 mL	194.3408 mL
5 mM	0.7774 mL	3.8868 mL	7.7736 mL	38.8682 mL
10 mM	0.3887 mL	1.9434 mL	3.8868 mL	19.4341 mL
20 mM	0.1943 mL	0.9717 mL	1.9434 mL	9.7170 mL
50 mM	0.0777 mL	0.3887 mL	0.7774 mL	3.8868 mL
100 mM	0.0389 mL	0.1943 mL	0.3887 mL	1.9434 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc