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Anti-KLRG1 Antibody (3E456) is an antibody targeting KLRG1. Anti-KLRG1 Antibody (3E456) can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
| Description | Anti-KLRG1 Antibody (3E456) is an antibody targeting KLRG1. Anti-KLRG1 Antibody (3E456) can be used in ELISA,FCM. |
| Synonyms | MGC13600, MAFAL, MAFA, KLRG1, CLEC15AMAFA-LIKE, CLEC15A, 2F1 |
| Ig Type | Rabbit IgG |
| Clone | 3E456 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing A549 cells surface stained with TMAH-00673 (red line) at 1:100. The cells were incubated in 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | |
| Recommended Dose | FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human KLRG1 |
| Antigen Species | Human |
| Gene Name | KLRG1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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