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Adenosine N1-oxide

Name: Adenosine N1-oxide
Brand: TargetMol
SKU: T23636
Price: 61 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23636Cas No. 146-92-9

Alias ANO, Adenosine, 1-oxide, Adenosine N1 oxide, 1-Oxoadenosine

Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.

Adenosine N1-oxide

🥰Excellent

Purity: 99.9%

Catalog No. T23636Alias ANO, Adenosine, 1-oxide, Adenosine N1 oxide, 1-OxoadenosineCas No. 146-92-9

Pack Size	Price	Availability
1 mg	$61	In Stock
2 mg	$87	In Stock
5 mg	$123	In Stock
10 mg	$177	In Stock
25 mg	$319	In Stock
50 mg	$455	In Stock
100 mg	$669	In Stock
1 mL x 10 mM (in DMSO)	$126	In Stock

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Batch Information

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Purity:99.9%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.
Synonyms	ANO, Adenosine, 1-oxide, Adenosine N1 oxide, 1-Oxoadenosine

Chemical Properties

Molecular Weight	283.24
Formula	C₁₀H₁₃N₅O₅
Cas No.	146-92-9
Smiles	O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N(=O)=CN3)O[C@H](CO)[C@H]1O
Relative Density.	2.15 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (211.83 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5306 mL	17.6529 mL	35.3057 mL	176.5287 mL
5 mM	0.7061 mL	3.5306 mL	7.0611 mL	35.3057 mL
10 mM	0.3531 mL	1.7653 mL	3.5306 mL	17.6529 mL
20 mM	0.1765 mL	0.8826 mL	1.7653 mL	8.8264 mL
50 mM	0.0706 mL	0.3531 mL	0.7061 mL	3.5306 mL
100 mM	0.0353 mL	0.1765 mL	0.3531 mL	1.7653 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc