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Anti-TRXR1/TXNRD1 Antibody (3T212)
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Catalog No. TMAY-02473
Alias TXNR, TRXR1, TR1, TR, thioredoxin reductase 1, GRIM-12
Anti-TRXR1/TXNRD1 Antibody (3T212) is a Mouse antibody targeting TRXR1/TXNRD1. Anti-TRXR1/TXNRD1 Antibody (3T212) can be used in ICC/IF.
Anti-TRXR1/TXNRD1 Antibody (3T212)
Anti-TRXR1/TXNRD1 Antibody (3T212)
😃Good
Catalog No. TMAY-02473Alias TXNR, TRXR1, TR1, TR, thioredoxin reductase 1, GRIM-12
Anti-TRXR1/TXNRD1 Antibody (3T212) is a Mouse antibody targeting TRXR1/TXNRD1. Anti-TRXR1/TXNRD1 Antibody (3T212) can be used in ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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| Description | Anti-TRXR1/TXNRD1 Antibody (3T212) is a Mouse antibody targeting TRXR1/TXNRD1. Anti-TRXR1/TXNRD1 Antibody (3T212) can be used in ICC/IF. |
| Synonyms | TXNR, TRXR1, TR1, TR, thioredoxin reductase 1, GRIM-12 |
| Ig Type | Mouse IgG1 |
| Clone | 3T212 |
| Reactivity | Human |
| Specificity | Human Thioredoxin reductase 1/TRXR1 |
| Verified Activity | Immunofluorescence staining of Human TXNRD1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with mouse anti-Human TXNRD1 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody(green). Positive staining was localized to cytoplasm and nucleus. |
| Application | |
| Recommended Dose | ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TXNRD1 Protein (TMPY-02271) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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