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Geranyl acetate

🥰Excellent

Catalog No. T5607Cas No. 105-87-3

Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.

Geranyl acetate

🥰Excellent

Purity: 99.36%

Catalog No. T5607Cas No. 105-87-3

Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.

Pack Size	Price	Availability	Quantity
25 g	$31	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.36%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.
In vitro	Studies on the antifungal activity especially Microsporum gypsum, Trichophyton vercossum and Candida tropicalis showed that geranyl acetate, its epoxide and hydroperoxide derivatives have good antifungal action[1].Geranyl acetate exhibited significant anticancer activity against colo-205 cancer cell line with IC50 values of 30 μM . To find out the underlying mechanism, DAPI staining was carried out and it was observed that both the monoterpenes, geraniol and geranyl acetate, induced apoptosis in colo-205 cells. The apoptosis was also associated with upregulation of Bax and downregulation of Bcl-2 expressions, indicative of mitochondrial apoptosis. Moreover, this monoterpenes could trigger DNA damage and G2/M cell cycle arrest in colo-205 cells[1].
Cell Research	The antiproliferative activity was determined by MTT assay. Apoptosis was assessed by DAPI staining and DNA damage was checked by comet assay. The cell cycle analysis was carried out by flow cytometry and protein expression was examined by western blotting.[1].

Chemical Properties

Molecular Weight	196.29
Formula	C₁₂H₂₀O₂
Cas No.	105-87-3
Smiles	CC(C)=CCCC(C)=CCOC(C)=O
Relative Density.	0.91

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (127.36 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.0945 mL	25.4725 mL	50.9450 mL	254.7252 mL
5 mM	1.0189 mL	5.0945 mL	10.1890 mL	50.9450 mL
10 mM	0.5095 mL	2.5473 mL	5.0945 mL	25.4725 mL
20 mM	0.2547 mL	1.2736 mL	2.5473 mL	12.7363 mL
50 mM	0.1019 mL	0.5095 mL	1.0189 mL	5.0945 mL
100 mM	0.0509 mL	0.2547 mL	0.5095 mL	2.5473 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc