Powder: -20°C for 3 years | In solvent: -80°C for 1 year
M47, a small molecule, selectively targets and destabilizes Cryptochrome 1 (CRY1), promoting its degradation within the nucleus. This compound not only initiates apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines but also extends the lifespan of p53 knockout mice, indicating its potential application in cancer research [1].
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Description | M47, a small molecule, selectively targets and destabilizes Cryptochrome 1 (CRY1), promoting its degradation within the nucleus. This compound not only initiates apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines but also extends the lifespan of p53 knockout mice, indicating its potential application in cancer research [1]. |
Molecular Weight | 471.93 |
Formula | C28H22ClNO4 |
CAS No. | 890808-56-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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M47 890808-56-7 inhibitor inhibit