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Anti-LILRB1/CD85j/ILT2 Antibody (5D841)
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Catalog No. TMAY-02808
Alias XXbac-BCX85G21.4, MIR-7, MIR7, LIR-1, LIR1, leukocyte immunoglobulin like receptor B1, ILT-2, ILT2, CD85j
Anti-LILRB1/CD85j/ILT2 Antibody (5D841) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (5D841) can be used in FCM.
Anti-LILRB1/CD85j/ILT2 Antibody (5D841)
Anti-LILRB1/CD85j/ILT2 Antibody (5D841)
😃Good
Catalog No. TMAY-02808Alias XXbac-BCX85G21.4, MIR-7, MIR7, LIR-1, LIR1, leukocyte immunoglobulin like receptor B1, ILT-2, ILT2, CD85j
Anti-LILRB1/CD85j/ILT2 Antibody (5D841) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (5D841) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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| Description | Anti-LILRB1/CD85j/ILT2 Antibody (5D841) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (5D841) can be used in FCM. |
| Alias | XXbac-BCX85G21.4, MIR-7, MIR7, LIR-1, LIR1, leukocyte immunoglobulin like receptor B1, ILT-2, ILT2, CD85j |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5D841 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human LILRB1(CD85j) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB1(CD85j), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD85 / ILT2 / ILR1 / LILRB1 (rh CD85 / ILT2 / ILR1 / LILRB1; TMPY-03995; ADJ55949.1; Met1-His458). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia. |
| Conjucates | Unconjugated |
| Others Formats | PE |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human CD85 / ILT2 / ILR1 / LILRB1 Protein (TMPY-03995) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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