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TOPBioactivityRelated Conjugates and FormulationsAntigen DetailsChemical infoStorage&SolubilityCalculator

Anti-LILRB1/CD85j/ILT2 Antibody (5D841)

😃Good
Catalog No. TMAY-02808
Alias XXbac-BCX85G21.4, MIR-7, MIR7, LIR-1, LIR1, leukocyte immunoglobulin like receptor B1, ILT-2, ILT2, CD85j

Anti-LILRB1/CD85j/ILT2 Antibody (5D841) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (5D841) can be used in FCM.

Anti-LILRB1/CD85j/ILT2 Antibody (5D841)

Anti-LILRB1/CD85j/ILT2 Antibody (5D841)

😃Good
Catalog No. TMAY-02808Alias XXbac-BCX85G21.4, MIR-7, MIR7, LIR-1, LIR1, leukocyte immunoglobulin like receptor B1, ILT-2, ILT2, CD85j
Anti-LILRB1/CD85j/ILT2 Antibody (5D841) is a Mouse antibody targeting LILRB1/CD85j/ILT2. Anti-LILRB1/CD85j/ILT2 Antibody (5D841) can be used in FCM.
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100 μL$198 7-10 days
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Instruction Manual of Detection Antibody
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: FCM

Reactivity: Human
AliasXXbac-BCX85G21.4, MIR-7, MIR7, LIR-1, LIR1, leukocyte immunoglobulin like receptor B1, ILT-2, ILT2, CD85j
Ig Type
Mouse IgG1
Clone
5D841
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human LILRB1(CD85j) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB1(CD85j), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
Application
FCM
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD85 / ILT2 / ILR1 / LILRB1 (rh CD85 / ILT2 / ILR1 / LILRB1; TMPY-03995; ADJ55949.1; Met1-His458). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
PE
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Protein: Human CD85 / ILT2 / ILR1 / LILRB1 Protein (TMPY-03995)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MIR 7LIR 1ILT 2
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