Sanggenone H

Name: Sanggenone H
Brand: TargetMol
SKU: TN2178
Rating: 4.5 (1 reviews)

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Catalog No. TN2178Cas No. 86450-80-8

Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α2 and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.

Sanggenone H

😃Good

Catalog No. TN2178Cas No. 86450-80-8

Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α2 and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.

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5 mg	$421	Inquiry	Inquiry

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Product Introduction

Bioactivity

Description	Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α± and IL-1α2 and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages.
In vitro	Chromatographic separation of root extracts of Morus alba and M. nigra led to the identification of the 2-arylbenzofurans moracin C (1), mulberrofuran Y (2), and mulberrofuran H (3), and the prenylated flavonoids kuwanon E (4), kuwanon C (5), Sanggenone H (6), cudraflavone B (7), and morusinol (8), and the Diels-Alder adducts soroceal (9), and sanggenon E (10).

Chemical Properties

Molecular Weight	354.35
Formula	C₂₀H₁₈O₆
Cas No.	86450-80-8
Smiles	OC1=C2C(=C(C=C1)[C@]3(OC=4C(C(=O)C3)=C(O)C=C(O)C4)[H])OC(C)(C)C=C2
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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