Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Umbralisib Tosylate (TGR-1202) is a potent, selectively dual inhibitor targeting PI3Kδ and casein kinase-1-ε (CK1ε), demonstrating oral activity. With EC50 values of 22.2 nM and 6.0 μM for PI3Kδ and CK1ε respectively, it shows unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL). This compound is utilized in the research of hematological malignancies.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Umbralisib Tosylate (TGR-1202) is a potent, selectively dual inhibitor targeting PI3Kδ and casein kinase-1-ε (CK1ε), demonstrating oral activity. With EC50 values of 22.2 nM and 6.0 μM for PI3Kδ and CK1ε respectively, it shows unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL). This compound is utilized in the research of hematological malignancies. |
Synonyms | RP5264 tosylate, TGR-1202 tosylate ; RP5264 tosylate, TGR-1202 tosylate |
Molecular Weight | 743.75 |
Formula | C38H32F3N5O6S |
CAS No. | 1532533-72-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Umbralisib tosylate 1532533-72-4 TGR-1202 tosylate ; RP 5264 Tosylate Umbralisib Tosylate RP5264 tosylate RP5264 Tosylate TGR-1202 tosylate ; RP5264 Tosylate TGR 1202 Tosylate TGR-1202 tosylate ; RP5264 tosylate TGR-1202 Tosylate TGR1202 Tosylate RP-5264 Tosylate TGR-1202 tosylate RP 5264 Tosylate TGR-1202 tosylate ; RP-5264 Tosylate inhibitor inhibit