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Anti-Filamin-A Antibody (7B270)
Catalog No. TMAH-00441 Copy Product Info
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Anti-Filamin-A Antibody (7B270) is an antibody targeting Filamin-A. Anti-Filamin-A Antibody (7B270) can be used in ELISA,IHC.
Anti-Filamin-A Antibody (7B270)
Copy Product Info🥰Excellent
Catalog No. TMAH-00441
Anti-Filamin-A Antibody (7B270) is an antibody targeting Filamin-A. Anti-Filamin-A Antibody (7B270) can be used in ELISA,IHC.
Anti-Filamin-A Antibody
(7B270)
(7B270)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Filamin-A Antibody (7B270) is an antibody targeting Filamin-A. Anti-Filamin-A Antibody (7B270) can be used in ELISA,IHC. |
| Ig Type | Rabbit IgG |
| Clone | 7B270 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00441 diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Perikaryon. Cell projection, growth cone. |
| Tissue Specificity | Ubiquitous. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking. Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance. During the axon guidance process, required for growth cone collapse induced by SEMA3A-mediated stimulation of neurons. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Filamin A |
| Antigen Species | Human |
| Gene Name | FLNA |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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