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Anti-ADGRE1 Antibody (6G833) is a Mouse antibody targeting ADGRE1. Anti-ADGRE1 Antibody (6G833) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $373 | 7-10 days |
Description | Anti-ADGRE1 Antibody (6G833) is a Mouse antibody targeting ADGRE1. Anti-ADGRE1 Antibody (6G833) can be used in WB. |
Alias | TM7LN3, Lymphocyte antigen 71, Ly71, Gpf480, F4/80, EMR1 hormone receptor, EMR1, EMR 1, EGFTM7, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EGF TM7, EGF like module receptor 1, Egf like module containing mucin like hormone receptor like sequence 1, Egf like module containing mucin like hormone receptor like 1, DD7A5 7, Cell surface glycoprotein F4/80, Cell surface glycoprotein EMR1, AGRE1, Adhesion G protein-coupled receptor E1 |
Ig Type | IgG |
Clone | 6G833 |
Reactivity | Human (predicted:Mouse,Rat) |
Verified Activity | Sample: Lane 1: Human HL-60 cell lysates Primary: Anti-ADGRE1 (F4/80) (TMAB-00062) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 95 kDa Observed band size: 120 kDa |
Application | WB |
Recommended Dose | WB: 1:100-1000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Cell membrane. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein G purified |
Appearance | Liquid |
Formulation | 0.01M PBS (pH7.4) with 0.1% BSA, 0.02% Proclin300. |
Research Background | The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages. |
Immunogen | KLH conjugated synthetic peptide: mouse F4/80 |
Antigen Species | Mouse |
Gene ID | |
Uniprot ID | |
Biology Area | Macrophage / Inflamm.,Other Cell Types |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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