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LTB4-IN-1

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Catalog No. T10917Cas No. 133012-00-7
Alias Anti-inflammatory agent 2

LTB4-IN-1 (Anti-inflammatory agent 2) with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4).

LTB4-IN-1

LTB4-IN-1

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Purity: 99.93%
Catalog No. T10917Alias Anti-inflammatory agent 2Cas No. 133012-00-7
LTB4-IN-1 (Anti-inflammatory agent 2) with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$291In StockIn Stock
5 mg$573In StockIn Stock
10 mg$972In StockIn Stock
25 mg$1,430In StockIn Stock
50 mg$1,950In StockIn Stock
100 mg$2,620In StockIn Stock
1 mL x 10 mM (in DMSO)$726In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.93%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
LTB4-IN-1 (Anti-inflammatory agent 2) with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4).
Targets&IC50
LTB4:70 nM
In vitro
Leukotriene acts as a mediator for various inflammatory and allergic conditions due to its various pro-inflammatory properties.
SynonymsAnti-inflammatory agent 2
Chemical Properties
Molecular Weight466.59
FormulaC26H30N2O4S
Cas No.133012-00-7
SmilesC(C(NS(C)(=O)=O)=O)(C1=CC=C(OCC2=NC3=C(C=C2)C=CC=C3)C=C1)C4CCCCCC4
Relative Density.1.243 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 125 mg/mL (267.9 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1432 mL10.7160 mL21.4321 mL107.1605 mL
5 mM0.4286 mL2.1432 mL4.2864 mL21.4321 mL
10 mM0.2143 mL1.0716 mL2.1432 mL10.7160 mL
20 mM0.1072 mL0.5358 mL1.0716 mL5.3580 mL
50 mM0.0429 mL0.2143 mL0.4286 mL2.1432 mL
100 mM0.0214 mL0.1072 mL0.2143 mL1.0716 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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