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SIRT5 inhibitor 2

🥰Excellent
Catalog No. T62032Cas No. 340306-87-8

SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with IC50=2.3 μM that has inhibitory activity through SIRT5-dependent deacetylation and can be used to study cancer and neurodegenerative diseases.

SIRT5 inhibitor 2

SIRT5 inhibitor 2

🥰Excellent
Purity: 99.87%
Catalog No. T62032Cas No. 340306-87-8
SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with IC50=2.3 μM that has inhibitory activity through SIRT5-dependent deacetylation and can be used to study cancer and neurodegenerative diseases.
Pack SizePriceAvailabilityQuantity
1 mg$293 In Stock
5 mg$722 In Stock
10 mg$987 In Stock
25 mg$1,520 In Stock
50 mg$1,980 In Stock
100 mg$2,500 In Stock
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Purity:99.87%
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Product Introduction

Bioactivity
Description
SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with IC50=2.3 μM that has inhibitory activity through SIRT5-dependent deacetylation and can be used to study cancer and neurodegenerative diseases.
Targets&IC50
SIRT5:2.3 μM
In vitro
SIRT5 inhibitor 2 (compound 49) is a selective inhibitor of SIRT5, showing an IC₅₀ of 2.3 μM. SIRT5 inhibitor 2 effectively blocks SIRT5-mediated desuccinylation and is applicable in studies related to cancer and neurodegenerative disorders [1].
Chemical Properties
Molecular Weight407.27
FormulaC18H12Cl2N2O3S
Cas No.340306-87-8
SmilesO=C1NC(=S)N(C(=O)C1=CC=2OC(=CC2)C=3C=CC=C(Cl)C3Cl)CC=C
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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