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SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with IC50=2.3 μM that has inhibitory activity through SIRT5-dependent deacetylation and can be used to study cancer and neurodegenerative diseases.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $722 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,520 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,500 | In Stock |
Description | SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with IC50=2.3 μM that has inhibitory activity through SIRT5-dependent deacetylation and can be used to study cancer and neurodegenerative diseases. |
Targets&IC50 | SIRT5:2.3 μM |
In vitro | SIRT5 inhibitor 2 (compound 49) is a selective inhibitor of SIRT5, showing an IC₅₀ of 2.3 μM. SIRT5 inhibitor 2 effectively blocks SIRT5-mediated desuccinylation and is applicable in studies related to cancer and neurodegenerative disorders [1]. |
Molecular Weight | 407.27 |
Formula | C18H12Cl2N2O3S |
Cas No. | 340306-87-8 |
Smiles | O=C1NC(=S)N(C(=O)C1=CC=2OC(=CC2)C=3C=CC=C(Cl)C3Cl)CC=C |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
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