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Vulinacimab

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Catalog No. T76954Cas No. 2250342-36-8
Alias HLX-06

Vulinacimab (REGN910, SAR153192) is a humanized monoclonal antibody targeting Vascular Endothelial Growth Factor Receptor 2 (VEGFR2). By binding with high affinity to VEGFR2, it blocks the interaction of various ligands, including VEGF-A, with the receptor, thereby inhibiting downstream pro-angiogenic and pro-survival signaling pathways. It is a key tool for studying tumor angiogenesis and VEGFR2-related pathologies.

Vulinacimab

Vulinacimab

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Catalog No. T76954Alias HLX-06Cas No. 2250342-36-8
Vulinacimab (REGN910, SAR153192) is a humanized monoclonal antibody targeting Vascular Endothelial Growth Factor Receptor 2 (VEGFR2). By binding with high affinity to VEGFR2, it blocks the interaction of various ligands, including VEGF-A, with the receptor, thereby inhibiting downstream pro-angiogenic and pro-survival signaling pathways. It is a key tool for studying tumor angiogenesis and VEGFR2-related pathologies.
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5 mgInquiryInquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Vulinacimab (REGN910, SAR153192) is a humanized monoclonal antibody targeting Vascular Endothelial Growth Factor Receptor 2 (VEGFR2). By binding with high affinity to VEGFR2, it blocks the interaction of various ligands, including VEGF-A, with the receptor, thereby inhibiting downstream pro-angiogenic and pro-survival signaling pathways. It is a key tool for studying tumor angiogenesis and VEGFR2-related pathologies.
SynonymsHLX-06
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetVEGFR-2
Chemical Properties
Cas No.2250342-36-8
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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