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Vulinacimab (REGN910, SAR153192) is a humanized monoclonal antibody targeting Vascular Endothelial Growth Factor Receptor 2 (VEGFR2). By binding with high affinity to VEGFR2, it blocks the interaction of various ligands, including VEGF-A, with the receptor, thereby inhibiting downstream pro-angiogenic and pro-survival signaling pathways. It is a key tool for studying tumor angiogenesis and VEGFR2-related pathologies.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 5 mg | Inquiry | Inquiry | Inquiry |
| Description | Vulinacimab (REGN910, SAR153192) is a humanized monoclonal antibody targeting Vascular Endothelial Growth Factor Receptor 2 (VEGFR2). By binding with high affinity to VEGFR2, it blocks the interaction of various ligands, including VEGF-A, with the receptor, thereby inhibiting downstream pro-angiogenic and pro-survival signaling pathways. It is a key tool for studying tumor angiogenesis and VEGFR2-related pathologies. |
| Synonyms | HLX-06 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | VEGFR-2 |
| Cas No. | 2250342-36-8 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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