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Ivonescimab

😃Good
Catalog No. T77046Cas No. 2428381-53-5
Alias SMT-112, SMT112, AK112, AK 112

Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC).

Ivonescimab

Ivonescimab

😃Good
Purity: 95%
Catalog No. T77046Alias SMT-112, SMT112, AK112, AK 112Cas No. 2428381-53-5
Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$415In StockIn Stock
5 mg$1,070-In Stock
10 mg$1,660-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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Product Introduction

Bioactivity
Description
Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC).
SynonymsSMT-112, SMT112, AK112, AK 112
Reactivity
Human
Verified Activity
Immobilized Human VEGF Protein at 2 μg/mL can bind Ivonescimab. The EC50 is 0.02260 μg/mL.

Immobilized Human PD-1 Protein (His) at 2 μg/mL can bind Ivonescimab. The EC50 is 0.07388 μg/mL.
verifiedActivityverifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetVEGFA & PDCD1
Chemical Properties
Molecular Weight201.12 kDa
Cas No.2428381-53-5
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeHuman IgG1-LALA kappa
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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