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Ivonescimab (Synonyms: SMT-112, SMT112, AK112, AK 112)

Catalog No. T77046 Copy Product Info
Purity: 95%
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Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC).

Ivonescimab

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🥰Excellent
Catalog No. T77046
Synonyms SMT-112, SMT112, AK112, AK 112

Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC).

Ivonescimab
Cas No. 2428381-53-5
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$415In StockIn Stock
5 mg$1,070-In Stock
10 mg$1,660-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC).
SynonymsSMT-112, SMT112, AK112, AK 112
Reactivity
Human
Verified Activity
Immobilized Human VEGF Protein at 2 μg/mL can bind Ivonescimab. The EC50 is 0.02260 μg/mL.
Immobilized Human PD-1 Protein (His) at 2 μg/mL can bind Ivonescimab. The EC50 is 0.07388 μg/mL.
verifiedActivityverifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetVEGFA & PDCD1
Chemical Properties
Molecular Weight201.12 kDa
Cas No.2428381-53-5
Antibody Information
IsotypeHuman IgG1-LALA kappa
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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