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Ivonescimab
(Synonyms: SMT-112, SMT112, AK112, AK 112) Copy Product Info
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Synonyms: SMT-112, SMT112, AK112, AK 112
Catalog No. T77046 Copy Product Info
Purity: 95%
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Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC).
Ivonescimab
Cas No. 2428381-53-5
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $415 | In Stock | In Stock | |
| 5 mg | $1,070 | - | In Stock | |
| 10 mg | $1,660 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
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Storage & Solubility Information
| Description | Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, used for the treatment of non-small cell lung cancer (NSCLC). |
| Synonyms | SMT-112, SMT112, AK112, AK 112 |
| Reactivity | Human |
| Verified Activity | Immobilized Human VEGF Protein at 2 μg/mL can bind Ivonescimab. The EC50 is 0.02260 μg/mL.
Immobilized Human PD-1 Protein (His) at 2 μg/mL can bind Ivonescimab. The EC50 is 0.07388 μg/mL.  , |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | VEGFA & PDCD1 |
| Molecular Weight | 201.12 kDa |
| Cas No. | 2428381-53-5 |
| Isotype | Human IgG1-LALA kappa |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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