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N-acetyl Leukotriene E4

Name: N-acetyl Leukotriene E4
Brand: TargetMol
SKU: T38062
Rating: 4.5 (1 reviews)

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Catalog No. T38062Cas No. 80115-95-3

Alias N-Acetyl-LTE4

N-acetyl Leukotriene E4 is an endogenous metabolite of Leukotriene E4, which is excreted mainly through bile, and is one to three orders of magnitude less active than Leukotriene E4, causing constriction of the airways.

N-acetyl Leukotriene E4

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Catalog No. T38062Alias N-Acetyl-LTE4Cas No. 80115-95-3

Pack Size	Price	USA Warehouse	Global Warehouse
25 μg	$598	35 days	35 days
50 μg	$1,130	35 days	35 days
100 μg	$2,130	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Appearance:Liquid

Color:Transparent

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COA

Product Introduction

Bioactivity

Description	N-acetyl Leukotriene E4 is an endogenous metabolite of Leukotriene E4, which is excreted mainly through bile, and is one to three orders of magnitude less active than Leukotriene E4, causing constriction of the airways.
Synonyms	N-Acetyl-LTE4

Chemical Properties

Molecular Weight	481.65
Formula	C₂₅H₃₉NO₆S
Cas No.	80115-95-3
Smiles	O=C(O)CCCC(O)C(SCC(NC(=O)C)C(=O)O)C=CC=CC=CCC=CCCCCC

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS pH 7.2: < 1 mg/mL (insoluble)

DMF: 20 mg/mL (41.52 mM), Sonication is recommended.

Ethanol: 20 mg/mL (41.52 mM), Sonication is recommended.

DMSO: 20 mg/mL (41.52 mM), Sonication is recommended.

Solution Preparation Table

DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0762 mL	10.3810 mL	20.7620 mL	103.8098 mL
5 mM	0.4152 mL	2.0762 mL	4.1524 mL	20.7620 mL
10 mM	0.2076 mL	1.0381 mL	2.0762 mL	10.3810 mL
20 mM	0.1038 mL	0.5190 mL	1.0381 mL	5.1905 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc