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VEGFR-IN-1

Name: VEGFR-IN-1
Brand: TargetMol
SKU: T23504
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T23504Cas No. 269390-69-4

Alias VEGFR Tyrosine Kinase Inhibitor II

VEGFR inhibitor

VEGFR-IN-1

🥰Excellent

Catalog No. T23504Alias VEGFR Tyrosine Kinase Inhibitor IICas No. 269390-69-4

VEGFR inhibitor

Product information is being updated, if you want to purchase, please click the bulk custom button.

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Product Introduction

Bioactivity

Description	VEGFR inhibitor
Targets&IC50	KDR:0.02 μM (IC50), FLK1:0.18 μM (IC50), EGFR:0.24 μM (IC50)
Synonyms	VEGFR Tyrosine Kinase Inhibitor II

Chemical Properties

Molecular Weight	337.8
Formula	C₁₉H₁₆ClN₃O
Cas No.	269390-69-4
Relative Density.	1.331 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (148.02 mM), Sonication is recommended.

Ethanol: ≤25 mg/mL, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9603 mL	14.8017 mL	29.6033 mL	148.0166 mL
5 mM	0.5921 mL	2.9603 mL	5.9207 mL	29.6033 mL
10 mM	0.2960 mL	1.4802 mL	2.9603 mL	14.8017 mL
20 mM	0.1480 mL	0.7401 mL	1.4802 mL	7.4008 mL
50 mM	0.0592 mL	0.2960 mL	0.5921 mL	2.9603 mL
100 mM	0.0296 mL	0.1480 mL	0.2960 mL	1.4802 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc