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3-Hydroxydodecanoic acid

Name: 3-Hydroxydodecanoic acid
Brand: TargetMol
SKU: T19120
Price: 38 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19120Cas No. 1883-13-2

3-Hydroxydodecanoic acid is a long-chain fatty acid and endogenous metabolite that accumulates in rat brains, inducing oxidative stress, lipid peroxidation, and protein oxidative damage, while reducing GSH levels, making it useful for studying neurological symptoms.

3-Hydroxydodecanoic acid

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Purity: 98%

Catalog No. T19120Cas No. 1883-13-2

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$38	-	In Stock
5 mg	$60	-	In Stock
10 mg	$98	-	In Stock
25 mg	$197	-	In Stock
50 mg	$293	-	In Stock
100 mg	$435	-	In Stock
200 mg	$629	-	In Stock
1 mL x 10 mM (in DMSO)	$67	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:98%

Appearance:Solid

Color:White

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COA HNMR

Product Introduction

Bioactivity

Description	3-Hydroxydodecanoic acid is a long-chain fatty acid and endogenous metabolite that accumulates in rat brains, inducing oxidative stress, lipid peroxidation, and protein oxidative damage, while reducing GSH levels, making it useful for studying neurological symptoms.
In vitro	Methods: 3-Hydroxydodecanoic acid (1-100 μM, 1 h) was used to treat thiobarbituric acid-reactive substances (TBA-RS) in rat cerebral cortex homogenate and its effects were observed. Results: 3-Hydroxydodecanoic acid induced lipid peroxidation in rat cerebral cortex and increased the level of TBA-RS. [1]

Chemical Properties

Molecular Weight	216.32
Formula	C₁₂H₂₄O₃
Cas No.	1883-13-2
Smiles	O=C(O)CC(O)CCCCCCCCC
Relative Density.	0.987 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (369.82 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (15.26 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.6228 mL	23.1139 mL	46.2278 mL	231.1391 mL
5 mM	0.9246 mL	4.6228 mL	9.2456 mL	46.2278 mL
10 mM	0.4623 mL	2.3114 mL	4.6228 mL	23.1139 mL
20 mM	0.2311 mL	1.1557 mL	2.3114 mL	11.5570 mL
50 mM	0.0925 mL	0.4623 mL	0.9246 mL	4.6228 mL
100 mM	0.0462 mL	0.2311 mL	0.4623 mL	2.3114 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc