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9(S)-HODE

Catalog No. T36727 CAS 73543-67-6

9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.[1],[2] It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles.[3]

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9(S)-HODE, CAS 73543-67-6

Pack Size	Availability	Price/USD
5 mg	6-8 weeks	$ 970.00 $ 776.00
50 mg	6-8 weeks	$ 1,980.00 $ 1,584.00
100 mg	6-8 weeks	$ 2,500.00 $ 2,000.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	296.44
Formula	C18H32O3
CAS No.	73543-67-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE)

DMSO: >50 mg/mL (per Rao Maddipati)

DMF: >50 mg/mL (per Rao Maddipati)

Ethanol: >50 mg/mL (per Rao Maddipati)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Gardner, H.W. Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism Biochim. Biophys. Acta 1001(3), 274-281 (1989). 2. Kühn, H., Belkner, J., and Wiesner, R. Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes Eur. J. Biochem. 191(1), 221-227 (1990). 3. Ku, G., Thomas, C.E., Akeson, A.L., et al. Induction of interleukin 1β expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid J. Biol. Chem. 267(20), 14183-14188 (1992).

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

9(S)-HODE 73543-67-6 9(S)HODE 9(S) HODE inhibitor inhibit

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