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Letaxaban

Name: Letaxaban
Brand: TargetMol
SKU: T68092
Price: 147 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T68092Cas No. 870262-90-1

Alias TAK-442

Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.

Letaxaban

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Purity: 99.87%

Catalog No. T68092Alias TAK-442Cas No. 870262-90-1

Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.

Pack Size	Price	Availability
1 mg	$147	In Stock
5 mg	$378	In Stock
10 mg	$545	In Stock
25 mg	$826	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.87%

ee:100%

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COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description	Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.
Synonyms	TAK-442

Chemical Properties

Molecular Weight	479.98
Formula	C₂₂H₂₆ClN₃O₅S
Cas No.	870262-90-1
Smiles	ClC1=CC2=C(C=C(S(C[C@H](C(=O)N3CCC(CC3)N4C(=O)NCCC4)O)(=O)=O)C=C2)C=C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (104.17 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0834 mL	10.4171 mL	20.8342 mL	104.1710 mL
5 mM	0.4167 mL	2.0834 mL	4.1668 mL	20.8342 mL
10 mM	0.2083 mL	1.0417 mL	2.0834 mL	10.4171 mL
20 mM	0.1042 mL	0.5209 mL	1.0417 mL	5.2086 mL
50 mM	0.0417 mL	0.2083 mL	0.4167 mL	2.0834 mL
100 mM	0.0208 mL	0.1042 mL	0.2083 mL	1.0417 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc