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(4R)-RO5263397

🥰Excellent
Catalog No. T12745LCas No. 1357266-80-8

(4R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamin was active against TRACE AMINE ASSOCIATED RECEPTOR (TAAR 1) with an EC50 of 0.017 μM and could be used to study neurological disorders.

(4R)-RO5263397
Other Forms of (4R)-RO5263397:

(4R)-RO5263397

🥰Excellent
Purity: 98.21%
Catalog No. T12745LCas No. 1357266-80-8
(4R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamin was active against TRACE AMINE ASSOCIATED RECEPTOR (TAAR 1) with an EC50 of 0.017 μM and could be used to study neurological disorders.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$83In StockIn Stock
5 mg$201In StockIn Stock
10 mg$273In StockIn Stock
25 mg$415In StockIn Stock
50 mg$559In StockIn Stock
100 mg$735In StockIn Stock
200 mg$973-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:98.21%
ee:100%
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COA FNMR HNMR CSFC LCMS ORP

Product Introduction

Bioactivity
Description
(4R)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamin was active against TRACE AMINE ASSOCIATED RECEPTOR (TAAR 1) with an EC50 of 0.017 μM and could be used to study neurological disorders.
Chemical Properties
Molecular Weight194.21
FormulaC10H11FN2O
Cas No.1357266-80-8
SmilesCc1c(F)cccc1[C@@H]1COC(N)=N1
Relative Density.1.32 g/cm3 (Predicted)
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (257.45 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.1491 mL25.7453 mL51.4907 mL257.4533 mL
5 mM1.0298 mL5.1491 mL10.2981 mL51.4907 mL
10 mM0.5149 mL2.5745 mL5.1491 mL25.7453 mL
20 mM0.2575 mL1.2873 mL2.5745 mL12.8727 mL
50 mM0.1030 mL0.5149 mL1.0298 mL5.1491 mL
100 mM0.0515 mL0.2575 mL0.5149 mL2.5745 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

RO-5263397RO5263397RO 5263397(4R)4(3Fluoro2methylphenyl)4,5dihydro2oxazolamine
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