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L-Glutamic acid

🥰Excellent
Catalog No. T2A2497Cas No. 56-86-0
Alias glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acid

L-Glutamic acid is an excitatory amino acid neurotransmitter and a Glutamic acid receptor agonist, including metabolic glutamic acid receptor (mGluR), AMPA receptor, NMDA receptor and KA receptor. L-Glutamic acid has an excitatory effect on the process of DA release from dopaminergic nerve endings. L-Glutamic acid can be used in the research of neurological diseases. L-Glutamic acid acts on ionic and metabolic Glutamic acid receptors.

L-Glutamic acid

L-Glutamic acid

🥰Excellent
Purity: 99.55%
Catalog No. T2A2497Alias glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acidCas No. 56-86-0
L-Glutamic acid is an excitatory amino acid neurotransmitter and a Glutamic acid receptor agonist, including metabolic glutamic acid receptor (mGluR), AMPA receptor, NMDA receptor and KA receptor. L-Glutamic acid has an excitatory effect on the process of DA release from dopaminergic nerve endings. L-Glutamic acid can be used in the research of neurological diseases. L-Glutamic acid acts on ionic and metabolic Glutamic acid receptors.
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5 g$42In Stock
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Purity:99.55%
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Product Introduction

Bioactivity
Description
L-Glutamic acid is an excitatory amino acid neurotransmitter and a Glutamic acid receptor agonist, including metabolic glutamic acid receptor (mGluR), AMPA receptor, NMDA receptor and KA receptor. L-Glutamic acid has an excitatory effect on the process of DA release from dopaminergic nerve endings. L-Glutamic acid can be used in the research of neurological diseases. L-Glutamic acid acts on ionic and metabolic Glutamic acid receptors.
Targets&IC50
HEK293 cells:0.06 μM, CHO cells:1.2 μM, BHK-21 cells:1.8 μM (EC50), Oocyte:0.45 μM
In vitro
METHODS: SH-SY5Y cells were treated with L-Glutamic acid (10, 20, 30 mM) for 3 hours, and cell viability was detected using the MTT assay.
RESULTS: L-Glutamic acid reduced the viability of SH-SY5Y cells. [1]
Synonymsglutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acid
Chemical Properties
Molecular Weight147.13
FormulaC5H9NO4
Cas No.56-86-0
Smiles[C@H](CCC(O)=O)(C(O)=O)N
Relative Density.1.54 g/cm3. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 8.33 mg/mL (56.62 mM), Sonication is recommended.
DMSO: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM6.7967 mL33.9836 mL67.9671 mL339.8355 mL
5 mM1.3593 mL6.7967 mL13.5934 mL67.9671 mL
10 mM0.6797 mL3.3984 mL6.7967 mL33.9836 mL
20 mM0.3398 mL1.6992 mL3.3984 mL16.9918 mL
50 mM0.1359 mL0.6797 mL1.3593 mL6.7967 mL

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