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L-Glutamic acid
🥰Excellent
Catalog No. T2A2497Cas No. 56-86-0
Alias glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acid
L-Glutamic acid is an excitatory amino acid neurotransmitter and a Glutamic acid receptor agonist, including metabolic glutamic acid receptor (mGluR), AMPA receptor, NMDA receptor and KA receptor. L-Glutamic acid has an excitatory effect on the process of DA release from dopaminergic nerve endings. L-Glutamic acid can be used in the research of neurological diseases. L-Glutamic acid acts on ionic and metabolic Glutamic acid receptors.
L-Glutamic acid
🥰Excellent
Purity: 99.55%
Catalog No. T2A2497Alias glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acidCas No. 56-86-0
L-Glutamic acid is an excitatory amino acid neurotransmitter and a Glutamic acid receptor agonist, including metabolic glutamic acid receptor (mGluR), AMPA receptor, NMDA receptor and KA receptor. L-Glutamic acid has an excitatory effect on the process of DA release from dopaminergic nerve endings. L-Glutamic acid can be used in the research of neurological diseases. L-Glutamic acid acts on ionic and metabolic Glutamic acid receptors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 g | $42 | In Stock |
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Purity:99.55%
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Product Introduction
Bioactivity
Chemical Properties
| Description | L-Glutamic acid is an excitatory amino acid neurotransmitter and a Glutamic acid receptor agonist, including metabolic glutamic acid receptor (mGluR), AMPA receptor, NMDA receptor and KA receptor. L-Glutamic acid has an excitatory effect on the process of DA release from dopaminergic nerve endings. L-Glutamic acid can be used in the research of neurological diseases. L-Glutamic acid acts on ionic and metabolic Glutamic acid receptors. |
| Targets&IC50 | HEK293 cells:0.06 μM, Oocyte:0.45 μM, BHK-21 cells:1.8 μM (EC50), CHO cells:1.2 μM |
| In vitro | METHODS: SH-SY5Y cells were treated with L-Glutamic acid (10, 20, 30 mM) for 3 hours, and cell viability was detected using the MTT assay. RESULTS: L-Glutamic acid reduced the viability of SH-SY5Y cells. [1] |
| Synonyms | glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acid |
| Molecular Weight | 147.13 |
| Formula | C5H9NO4 |
| Cas No. | 56-86-0 |
| Smiles | [C@H](CCC(O)=O)(C(O)=O)N |
| Relative Density. | 1.54 g/cm3. Temperature:20 °C. |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | H2O: 8.27 mg/mL (56.21 mM), Sonication is recommended.  DMSO: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
H2O
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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