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Synonyms: β-Defensin 1, HBD-1, HBD1, Defensin β1, Defensin Beta 1, DEFB1, Beta-Defensin 1, BD-1, BD1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-DEFB1 Antibody (9U174) is an antibody targeting DEFB1. Anti-DEFB1 Antibody (9U174) can be used in ELISA,FCM. |
| Synonyms | β-Defensin 1, HBD-1, HBD1, Defensin β1, Defensin Beta 1, DEFB1, Beta-Defensin 1, BD-1, BD1 |
| Ig Type | Rabbit IgG |
| Clone | 9U174 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. Membrane. |
| Tissue Specificity | Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human DEFB1 |
| Antigen Species | Human |
| Gene Name | DEFB1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Microbiology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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