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Anti-DEFB1 Antibody (9U174)
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Catalog No. TMAH-00340
Alias β-Defensin 1, HBD-1, HBD1, Defensin β1, Defensin Beta 1, DEFB1, Beta-Defensin 1, BD-1, BD1
Anti-DEFB1 Antibody (9U174) is an antibody targeting DEFB1. Anti-DEFB1 Antibody (9U174) can be used in ELISA,FCM.
Anti-DEFB1 Antibody (9U174)
Anti-DEFB1 Antibody (9U174)
😃Good
Catalog No. TMAH-00340Alias β-Defensin 1, HBD-1, HBD1, Defensin β1, Defensin Beta 1, DEFB1, Beta-Defensin 1, BD-1, BD1
Anti-DEFB1 Antibody (9U174) is an antibody targeting DEFB1. Anti-DEFB1 Antibody (9U174) can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-DEFB1 Antibody (9U174) is an antibody targeting DEFB1. Anti-DEFB1 Antibody (9U174) can be used in ELISA,FCM. |
| Synonyms | β-Defensin 1, HBD-1, HBD1, Defensin β1, Defensin Beta 1, DEFB1, Beta-Defensin 1, BD-1, BD1 |
| Ig Type | Rabbit IgG |
| Clone | 9U174 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing HepG2 cells surface stained with TMAH-00340 (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | |
| Recommended Dose | FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. Membrane. |
| Tissue Specificity | Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human DEFB1 |
| Antigen Species | Human |
| Gene Name | DEFB1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Microbiology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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