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Anti-ALK-1 Antibody (9Y73) (Synonyms: TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activ...)

Catalog No. TMAH-00024 Copy Product Info
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Anti-ALK-1 Antibody (9Y73) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (9Y73) can be used in ELISA,IHC,WB.

Anti-ALK-1 Antibody (9Y73)

Copy Product Info
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Catalog No. TMAH-00024
Synonyms TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1

Anti-ALK-1 Antibody (9Y73) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (9Y73) can be used in ELISA,IHC,WB.

Anti-ALK-1 Antibody
(9Y73)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ALK-1 Antibody (9Y73) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (9Y73) can be used in ELISA,IHC,WB.
SynonymsTSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1
Ig Type
Rabbit IgG
Clone
9Y73
Reactivity
Human
Verified Activity
1. Western Blot
-Positive WB detected in: Daudi whole cell lysate, U87 whole cell lysate
-All lanes: ACVRL1 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 57 kDa
-Observed band size: 65 kDa
2. IHC image of TMAH-00024 diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Application
Recommended Dose
WB:1:500-1:5000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type I membrane protein.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundType I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human ACVRL1
Antigen Species
Human
Gene Name
ACVRL1
Gene ID
Uniprot ID
Biology Area
Cancer, Cardiovascular, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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