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Anti-ALK-1 Antibody (9Y73)
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Catalog No. TMAH-00024
Alias TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1
Anti-ALK-1 Antibody (9Y73) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (9Y73) can be used in ELISA, WB, IHC.
Anti-ALK-1 Antibody (9Y73)
Anti-ALK-1 Antibody (9Y73)
😃Good
Catalog No. TMAH-00024Alias TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1
Anti-ALK-1 Antibody (9Y73) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (9Y73) can be used in ELISA, WB, IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | 196 € | 7-10 days | |
| 100 μL | 329 € | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ALK-1 Antibody (9Y73) is an antibody targeting ALK-1. Anti-ALK-1 Antibody (9Y73) can be used in ELISA, WB, IHC. |
| Alias | TSR-I, SKR3, ORW2, HHT2, HHT, ALK-1, ALK1, ACVRLK1, ACVRL1, activin A receptor type II-like 1 |
| Ig Type | Rabbit IgG |
| Clone | 9Y73 |
| Reactivity | Human |
| Verified Activity | 1. Western Blot -Positive WB detected in: Daudi whole cell lysate, U87 whole cell lysate -All lanes: ACVRL1 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 57 kDa -Observed band size: 65 kDa 2. IHC image of TMAH-00024 diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | ELISA, WB, IHC |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ACVRL1 |
| Antigen Species | Human |
| Gene ID | 94 |
| Uniprot ID | |
| Biology Area | Cancer, Cardiovascular, Metabolism, Signal transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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