Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Morin

Copy Product Info
😃Good
Catalog No. T2835Cas No. 480-16-0
Alias Toxylon pomiferum, Calico Yellow, Aurantica, Al-Morin

Morin (Calico Yellow) was found to be a weak inhibitor of fatty acid synthase (IC50: 2.33 μM). Morin is a yellow color substance that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).

Morin

Morin

Copy Product Info
😃Good
Purity: 96.82%
Catalog No. T2835Alias Toxylon pomiferum, Calico Yellow, Aurantica, Al-MorinCas No. 480-16-0
Morin (Calico Yellow) was found to be a weak inhibitor of fatty acid synthase (IC50: 2.33 μM). Morin is a yellow color substance that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$39In StockIn Stock
10 mg$55In StockIn Stock
25 mg$105In StockIn Stock
50 mg$155In StockIn Stock
100 mg$233-In Stock
1 mL x 10 mM (in DMSO)$43In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:96.82%
Appearance:Solid
Color:White to Yellow
Contact us for more batch information

Resource Download

Product Introduction

Morin AI Summary
Morin exhibits a diverse range of bioactivities across various biological targets and systems. It functions as an antimicrobial agent with activity against bacteria such as Proteus mirabilis, Staphylococcus aureus, and Pseudomonas aeruginosa, showing MIC values of 120.0 µg/mL and against Escherichia coli with an MIC of 1380.0 µg/mL. It also demonstrates notable binding affinity to adenosine receptors A1, A2, and A3, with Ki values of 13800.0 nM, 17300.0 nM, and 34000.0 nM, respectively. Additionally, it inhibits HIV-integrase with IC50 values of 76500.0 nM for cleavage and 31700.0 nM for integration. Morin is an inhibitor of several enzymes, including Glyoxalase I (Ki = 30199.52 nM), Bovine trypsin (IC50 = 110800.0 nM), FabZ (IC50 = 8000.0 nM), FabI (IC50 = 5000.0 nM), and FabG (IC50 = 2300.0 nM). It also exhibits activity against Plasmodium falciparum with IC50 values of 110400.0 nM (chloroquine-sensitive NF54 strain) and 16100.0 nM (chloroquine-resistant K1 strain). The compound shows inhibition against URAT1-mediated urate uptake in HEK293 cells (IC50 = 2000.0 nM) and rat renal brush border membrane vesicles (IC50 = 18000.0 nM). In mitochondrial enzyme assays, Morin inhibits NADH oxidase (IC50 = 430.0 nM), succinoxidase (IC50 = 730.0 nM), and ATPase (IC50 = 120.0 nM). It also demonstrates low toxicity in Salmonella Typhimurium in Ames assays and significant antioxidant properties with an ABTS radical scavenging capacity equivalent to 0.83 mmol/L Trolox. The compound displays antiviral activity against HIV1, HCV, and SARS-CoV-2. Additionally, Morin inhibits enzyme activities such as BACE1 (IC50 = 21700.0 nM), SYK kinase (IC50 = 28000.0 nM), and SET7 (IC50 = 6020.0 nM). It also modulates the aggregation of amyloid beta peptides and inhibits beta amyloid fibril formation with IC50 values of 240.0 nM and 670.0 nM for beta amyloid (1-40) and (1-42), respectively. Overall, Morin exhibits broad-spectrum bioactivities, including antimicrobial, antiviral, anti-inflammatory, enzymatic inhibition, and antioxidant properties, making it a potential candidate for various therapeutic applications..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Morin (Calico Yellow) was found to be a weak inhibitor of fatty acid synthase (IC50: 2.33 μM). Morin is a yellow color substance that can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).
Targets&IC50
FASN:2.33 μM
SynonymsToxylon pomiferum, Calico Yellow, Aurantica, Al-Morin
Chemical Properties
Molecular Weight302.24
FormulaC15H10O7
Cas No.480-16-0
SmilesOc1ccc(c(O)c1)-c1oc2cc(O)cc(O)c2c(=O)c1O
Relative Density.1.799. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (165.43 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.62 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3086 mL16.5431 mL33.0863 mL165.4314 mL
5 mM0.6617 mL3.3086 mL6.6173 mL33.0863 mL
10 mM0.3309 mL1.6543 mL3.3086 mL16.5431 mL
20 mM0.1654 mL0.8272 mL1.6543 mL8.2716 mL
50 mM0.0662 mL0.3309 mL0.6617 mL3.3086 mL
100 mM0.0331 mL0.1654 mL0.3309 mL1.6543 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Morin | purchase Morin | Morin cost | order Morin | Morin chemical structure | Morin formula | Morin molecular weight