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STING agonist-3 trihydrochloride

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Catalog No. T13014L
Alias STING agonist-3 trihydrochloride (2138299-29-1 free base)

STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer.

STING agonist-3 trihydrochloride
Other Forms of STING agonist-3 trihydrochloride:
STING agonist-3T130142138299-29-1
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STING agonist-3 trihydrochloride

😃Good
Catalog No. T13014LAlias STING agonist-3 trihydrochloride (2138299-29-1 free base)
STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
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Product Introduction

Bioactivity
Description
STING agonist-3 trihydrochloride is a selective and non-nucleotide agonist of small-molecule STING(pEC50 and pEC50 of 7.5 and 9.5, respectively), has durable anti-tumor effect and tremendous potential to improve treatment of cancer.
In vitro
STING agonist-3 trihydrochloride exhibits activation of STING in cells(pEC50 of 7.5), this assay is determined using a luciferase reporter assay in human embryonic kidney cells (HEK293T) co-transfected with plasmids expressing STING and the enzyme firefly luciferase driven by the interferon stimulated response element promoter.In FRET assay, STING agonist-3 trihydrochloride exhibits a pIC50 value of 9.5. This is a competition binding assay which aims to determine the binding potency of molecules to the C-terminal Domain (CTD) of human STING.
SynonymsSTING agonist-3 trihydrochloride (2138299-29-1 free base)
Chemical Properties
Molecular Weight860.19
FormulaC37H45Cl3N12O6
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Keywords

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